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Chapter 56 – Unstable Angina and Non–ST Elevation Myocardial Infarction

Christopher P. Cannon,
Eugene Braunwald

  DEFINITION, 1178
  PATHOPHYSIOLOGY, 1178
  Thrombosis, 1178
  Platelet Activation and Aggregation, 1178

  CLINICAL PRESENTATION, 1179
  Clinical Examination, 1179
  Electrocardiography, 1179
  Markers of Cardiac Necrosis, 1180
  Laboratory Tests, 1180
  Noninvasive Testing, 1180
  Clinical Classification, 1181
  Imaging, 1182
  Coronary Arteriographic Findings, 1182

  RISK STRATIFICATION, 1182
  Methods of Risk Stratification, 1183
  Combined Risk Assessment Scores, 1184

  MEDICAL THERAPY, 1185
  General Measures, 1185
  Antithrombotic Therapy, 1185
  Anticoagulants, 1190

  TREATMENT STRATEGIES AND INTERVENTIONS, 1192
  Indications for Invasive Versus Conservative Management Strategies, 1193
  Other Therapies, 1193
  Summary: Acute Management of UA/NSTEMI, 1194
  Long-Term Secondary Prevention After UA/NSTEMI, 1194

  PRINZMETAL VARIANT ANGINA, 1195
  Mechanisms, 1196
  Clinical and Laboratory Findings, 1196
  Management, 1197
  Prognosis, 1198

  REFERENCES, 1198
  GUIDELINES,…