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Chapter 47 – Lipoprotein Disorders and Cardiovascular Disease

Jacques Genest,
Peter Libby

  LIPOPROTEIN TRANSPORT SYSTEM, 975
  Biochemistry of Lipids, 975
  Lipoproteins, Apolipoproteins, Receptors, and Processing Enzymes, 975
  Lipoprotein Metabolism and Transport, 978

  LIPOPROTEIN DISORDERS, 982
  Definitions, 982
  Genetic Lipoprotein Disorders, 982
  Triglyceride-Rich Lipoproteins, 983
  High-Density Lipoproteins, 985
  Secondary Causes of Hyperlipidemia and the Metabolic Syndrome, 985

  DRUGS THAT AFFECT LIPOPROTEIN METABOLISM, 986
  Bile Acid–Binding Resins, 986
  Hydroxymethylglutaryl–Coenzyme A Reductase Inhibitors (Statins), 987
  Cholesterol Absorption Inhibitors, 987
  Fibric Acid Derivatives (Fibrates), 987
  Nicotinic Acid (Niacin), 988
  Cholesteryl Ester Transfer Protein Inhibitors, 988
  Fish Oils, 989
  Phytosterols, 989

  CLINICAL TRIALS OF DRUGS AFFECTING LIPID METABOLISM, 989
  Secondary Prevention and Acute Coronary Syndromes, 989
  Treating High-Risk (Primary Prevention) Patients, 990
  Trials of Drugs Other Than Statins, 991

  APPROACH TO …