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Chapter 46 – Systemic Hypertension  :  Therapy

Norman M. Kaplan

  BENEFITS OF THERAPY, 955
  Threshold of Therapy, 955
  Systolic Pressure in Older Patients, 955
  Goal of Therapy, 956

  LIFESTYLE MODIFICATIONS, 956
  ANTIHYPERTENSIVE DRUG THERAPY, 959
  General Guidelines, 959
  Diuretics, 961
  Adrenergic Inhibitors, 963
  Direct Vasodilators, 965
  Inhibitors of the Renin-Angiotensin-Aldosterone System, 966
  Other Agents, 968

  SPECIAL THERAPEUTIC CONSIDERATIONS, 968
  THERAPY FOR HYPERTENSIVE CRISES, 970
  FUTURE PERSPECTIVES, 971
  REFERENCES, 971
  GUIDELINES, 972

Hypertension is the most common modifiable risk factor for cardiovascular diseases in the United States and other developed countries.[1] Its prevalence will continue to increase, both among the young because of increasing obesity and in older adults because of longer life expectancy. Despite it continuing to be the most common indication for nonpregnant adults to visit a physician, hypertension remains inadequately treated.[2]There are many reasons for this, especially physician …