Synonym:

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Pemphigoid

	▪	Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disease, and it predominantly affects the elderly
	▪	It is usually a chronic disease, with spontaneous exacerbations and remissions, which may be accompanied by significant morbidity
	▪	BP is associated with tissue-bound and circulating autoantibodies directed against the BP antigen 180 (BP180, BPAG2 or type XVII collagen) and the BP antigen 230 (BP230 or BPAG1), components of junctional adhesion complexes called hemidesmosomes that promote dermo-epidermal cohesion
	▪	The spectrum of clinical presentations is extremely broad. Characteristically, BP is an intensely pruritic eruption with widespread blister formation. In early stages, or in atypical variants of the disease, only excoriated, eczematous or urticarial lesions (either localized or generalized) are present
	▪	Diagnosis relies on immunopathologic examinations, …