While the extensive armamentarium available for treating AD provides many options for individualized care, it bespeaks of the lack of ideal therapies. Primary prevention of AD therefore represents a highly desirable goal. Several studies have investigated the effect of allergen avoidance during pregnancy, infancy, or both. Such investigations have typically focused on dietary allergens (particularly cow's milk and eggs) and dust mites. In general, these studies have shown a modest benefit with a low-allergen maternal diet during breastfeeding or infant formulas based on hydrolyzed milk products rather than cow's milk (no benefit from soy milk)^[57–60]. However, manipulated maternal diets during pregnancy have been associated with preterm labor and lower birthweights. One study^[60]combined dietary restriction with house dust mite reduction, making the role of each allergen unclear. Strict dietary restrictions for children with AD can have dire consequences, e.g. …