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PART VII – Thyroid

Chapter 72 – Anatomy and Development of the Thyroid

Mario De Felice,
Roberto Di Lauro

  Anatomy of the Thyroid Gland
  Gross Anatomy
  Blood Supply
  Anatomic Variants

  The Thyroid Follicle
  The Thyroid Cells
  Thyroid Follicular Cells
  C Cells
  Ultimobranchial Body–Derived Epithelial Cells

  Development of the Thyroid Gland
  Specification of the Thyroid Follicular Cells: The Thyroid Anlage
  Early Stages of Thyroid Morphogenesis: Budding, Migration, and Lobulation of the Thyroid Primordium
  Late Stages of Thyroid Morphogenesis: Functional Differentiation and Histogenesis
  Ultimobranchial Bodies Development
  Differentiation of C Cells

  Molecular Genetics of Thyroid Gland Development
  Animal Models
  Insights from Human Diseases

  Phylogenesis of the Thyroid Gland
Anatomy of the Thyroid Gland


The thyroid gland was first described by Galen (130–210 ad) in his work “De Voce.” The gland was named thyroid by Thomas Whorton (1614–1673) because of its proximity to the thyroid cartilage.[1]Despite …