/Genetic Basis of Gonadal and Genital Development/

Chapter 118 – Genetic Basis of Gonadal and Genital Development

Charmian A. Quigley,
Eric Vilain

Development of the Bipotential Gonads

		Embryology of the Bipotential Gonads and Primordial Reproductive Tracts
		Genetics of the Bipotential Gonads and Primordial Genitalia

Sex Determination (Development of Testis or Ovary)

		Embryology of Testis Development
		Genetics of Testis Development (Testis Determination)
		Embryology of Ovary Development
		Genetics of Ovary Development (Ovary Determination)
		Human Sex Determination: The Battle Continues (A Puzzle With Missing Pieces)

Sex Differentiation (Development of Male or Female Internal and External Genitalia)

		Embryology and Endocrinology of Male Sex Differentiation
		Genetics of Male Sex Differentiation
		Embryology and Endocrinology of Female Sex Differentiation
		Genetics of Female Sex Differentiation

Conclusions

Sex determination and differentiation are distinct, consecutive processes that follow the establishment of chromosomal sex at the time of gamete fertilization. These …