The human pineal gland is the most poorly understood endocrine organ. Although it has been described as a dispensable gland in humans, the pineal gland converts light information into a hormonal signal in the form of melatonin. Melatonin is a chronobiotic hormone with multiple pleomorphic actions. The hormone transmits information regarding day length which helps organize circadian and seasonal rhythms. The mammalian pineal gland plays numerous modulatory roles in the regulation of sleep, …