Harvey Cushing^[1,2] was the first to codify the symptom complex of obesity, diabetes, hirsutism, and adrenal hyperplasia, and to postulate that the basophilic adenomas found at autopsy in six of eight patients caused the disease that now bears his name. Shortly thereafter, Walters and colleagues^[3]identified the etiologic contribution of adrenal tumors and the therapeutic role of adrenalectomy. Over the ensuing century, our understanding of the …