/Lens/Clinical background 4-u1.0-B978-0-7020-2983-7..00030-9..DOCPDF Chapter 30 4-u1.0-B978-0-7020-2983-7..00030-9 4-u1.0-B978-0-7020-2983-7..00030-9 4-u1.0-B978-0-7020-2983-7..00030-9--s0015 Biochemical mechanisms of age-related cataract SECTION 4 4-u1.0-B978-0-7020-2983-7..00030-9--s0010 Lens hubsection 3 section Lens SECTION 4 4-u1.0-B978-0-7020-2983-7..00030-9 4-u1.0-B978-0-7020-2983-7..00030-9--s0010 Biochemical mechanisms of age-related cataract 4-u1.0-B978-0-7020-2983-7..X0001-0--s9 Biochemical mechanisms of age-related cataract text/html; charset=ISO-8859-1 Clinical background Chapter 30 chapter bookContent 4-u1.0-B978-0-7020-2983-7..X0001-0--s9 Clinical background 4-u1.0-B978-0-7020-2983-7..00030-9 4-u1.0-B978-0-7020-2983-7..X0001-0--s9 4-u1.0-B978-0-7020-2983-7..00030-9 4-u1.0-B978-0-7020-2983-7..00029-2--fr9000 5 4-u1.0-B978-0-7020-2983-7..00030-9--s0010 Chapter 30 Ocular Disease: Mechanisms and Management 978-0-7020-2983-7 Levin and Albert 1st
SECTION 4 – LensChapter 30 – Biochemical mechanisms of age-related cataractDavid C Beebe,
Ying-Bo Shui,
Nancy M Holekamp
Clinical backgroundA cataract is any opacification of the lens. Visually significant cataracts may be present at birth or may occur at any time thereafter, but incidence increases exponentially after 50 years of age.[1] Age-related cataracts are responsible for nearly half of all blindness worldwide.[2,3]As longevity increases, the impact of cataracts on society is expected to increase. At present, surgical removal of the lens opacity with implantation of an intraocular lens (IOL) is the standard of care throughout most of the world where cataract surgery is available. Although this is usually a safe and effective treatment, intraocular surgery is an expensive and technically challenging solution for such a widespread problem. Rare but serious surgical complications include intraocular infection and inflammation and swelling of the retina (cystoid macular edema). Secondary …