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SECTION 7 – Other



Chapter 54 – Phthisis bulbi

Ingo Schmack,
Hans E Völcker,
Hans E Grossniklaus

Clinical background

Key symptoms and signs

Phthisis bulbi represents an ocular end-stage disease of various causes and is defined by atrophy, shrinkage, and disorganization of the eyeball and intraocular contents (Box 54.1).[1,2] Subjective complaints depend on the etiology and severity of phthisis bulbi. Typical clinical symptoms and signs include chronic ocular hypotension (5 mmHg), a shrunken globe, pseudoenophthalmos, intraocular tissue fibrosis and scarring, vision loss, and recurrent episodes of intraocular irritation and pain.[3]

Box 54.1 

Definition–phthisis bulbi

Phthisis bulbi represents an ocular end-stage disease characterized by:
      Atrophy
      Shrinkage
      Disorganization of the eyeball and its intraocular contents