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Symptoms and signs

SO can present with diverse clinical presentations, and any bilateral uveitis following ocular surgery or trauma to an eye should alert the ophthalmologist to the possibility of this entity.

The onset of inflammation in the sympathizing eye has been reported to appear any time between 5 days and 66 years after the initial trauma.[1,3] However, 80% of patients manifest with symptoms and signs of intraocular inflammation within 3 months, and 90% show evidence of inflammation within 1 year of the time of the initial insult.[1]

Patients usually present with mild ocular pain, photophobia, epiphora, and blurring of vision. Their near vision may sometimes be compromised. The clinical signs may vary from a mild anterior uveitis to severe granulomatous panuveitis associated with moderate to severe vitritis.

Posterior-segment findings include papillitis, generalized retinal edema, and diffuse choroiditis. Small yellow-white lesions may be seen in the mid periphery of the retina and …