Determining the etiology of a particular uveitic syndrome may be a difficult task because of the wide array of diagnostic considerations. However, correct identification of the predominant anatomic location of a disease entity is helpful in narrowing the differential diagnosis. The SUN Working Group criteria were valuable in describing the four major classes of uveitis: (1) anterior uveitis; (2) intermediate uveitis; (3) posterior uveitis; and (4) panuveitis.

Etiologies of anterior uveitis include sarcoidosis, human leukocyte antigen (HLA)-B27-associated uveitis, syphilis, tuberculosis, and Lyme disease. Causes of intermediate uveitis also include sarcoidosis, syphilis, Lyme disease, and tuberculosis. However, entities more commonly associated with intermediate uveitis (cf. anterior uveitis) include multiple sclerosis (MS), human T-cell lymphotrophic virus-1 (HTLV-1), and primary intraocular lymphoma, which may masquerade as a chronic vitritis in an elderly patient (i.e., …