/Non-neoplastic and neoplastic disorders of the appendix/Fibrous obliteration of the appendiceal lumen (neural hyperplasia) - Gastrointestinal and Liver Pathology: Expert Consult

8 – Non-neoplastic and neoplastic disorders of the appendix

Dora Lam-Himlin, MD,
Elizabeth Montgomery, MD,
Michael Torbenson, MD

■ Fibrous obliteration of the appendiceal lumen (neural hyperplasia)

Clinical features

There are no specific features as this is typically an incidental finding in about one third of appendices excised for a variety of reasons.

FIBROUS OBLITERATION OF THE APPENDICEAL LUMEN (NEURAL HYPERPLASIA)—FACT SHEET

Definition

■ A spindle cell proliferation that fills and “obliterates” the appendix lumen, usually at the tip

Incidence and location

■ Found in about one third of excised appendices

Morbidity and mortality

■ None

Gender, race, and age distribution

■ All ages, without race or gender predisposition

Clinical features

■ Incidental finding in appendices excised for all reasons

Pathologic features

Gross findings

The tip of the appendix is usually affected and appears whitish on cut surface. The appendix is not enlarged and the serosa is normal.

Microscopic findings

Obliteration of the appendiceal lumen is …