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SUPERFICIAL AND DEEP DERMAL INFLAMMATION

Superficial and deep dermal inflammation may accompany a major reaction pattern, as occurs in discoid lupus erythematosus in which there is a concomitant lichenoid reaction pattern, and in photocontact allergic dermatitis in which there is a spongiotic reaction pattern in addition to the dermal inflammation. This pattern of inflammation may also occur in the absence of any of the six major reaction patterns already discussed. The predominant cell type is usually the lymphocyte but there may be a variable admixture of other cell types (Fig. 1.17). The often quoted mnemonic of diseases causing this pattern of inflammation is the eight ‘L’ diseases – light reactions, lymphoma (including pseudolymphomas), leprosy, lues (syphilis), lichen striatus, lupus erythematosus, lipoidica (includes necrobiosis lipoidica and incomplete forms of granuloma annulare), and lepidoptera (used incorrectly in the mnemonic to refer to arthropod bites and other parasitic …